Overview of the Alzheimer s disease pathology and potential therapeutic targets.- Trial designs and outcomes to monitor novel therapeutics in alzheimer s disease.- The pharmacological treatment of Alzheimer s disease with cholinesterase inhibitors and memantine.- M1 Muscarinic Agonists.- Cholinergic Neurodegeneration in Alzheimer s Disease: Basis for Nerve Growth Factor Therapy.- The rationale for glutamatergic therapy in Alzheimer s disease.- Secretases as pharmacological targets in Alzheimer s disease.- Secretase as a Target for Alzheimer s Disease.- The Rationale for an Immunological Approach to Alzheimer s Therapeutics.- Neuroinflammation, Alzheimer Disease and Other Aging Disorders.- Non-steroidal anti-inflammatory drugs (NSAIDs) and derived A42-lowering molecules for treatment and prevention of Alzheimer s disease (AD).- The potential application of antioxidant agents in Alzheimer disease therapeutics.- Apolipoprotein E: a potent gene-based therapeutic target for the treatment of sporadic Alzheimer s disease.- Tau Pathology as a Target In Alzheimer s Therapeutics.- Design of inhibitors of Amyloid-beta misfolding and aggregation for Alzheimer s Therapy.- Potential applications of glycosaminoglycan-related compounds in Alzheimer s disease.- Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease.- Interpreting Clinical Studies of Putative Therapeutics for Alzheimer s disease.
EAN/ISBN : 9780387715223
Publisher(s): Springer, Berlin, Springer, New York
Discussed keywords: Alzheimersche Krankheit
Format: ePub/PDF

Author(s): Cuello, A. Claudio